Absence of xanthine oxidase or xanthine dehydrogenase in the rabbit myocardium
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منابع مشابه
Absence of xanthine oxidase or xanthine dehydrogenase in the rabbit myocardium.
We directly measured the activity of the enzymes xanthine oxidase and xanthine dehydrogenase in rabbit and rat hearts, using a sensitive radiochemical assay. Neither xanthine oxidase activity nor xanthine dehydrogenase activity was detected in the rabbit heart. In the rat heart, xanthine oxidase activity was 9.1 +/- 0.5 mIU per gram wet weight and xanthine dehydrogenase activity was 53.0 +/- 1....
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The enzyme xanthine oxidase has been implicated as a generator of toxic oxygen metabolites that contribute to ischemic injury. Because substantial species variability has been demonstrated and because there are minimal human data available, the relevance of xanthine oxidase to human heart damage has been in doubt. We report the absence of xanthine oxidase activity in nine human heart biopsy spe...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 1986
ISSN: 0006-291X
DOI: 10.1016/s0006-291x(86)80157-7